TNS FC
| TNS FC | 2 - 1 | Yieke FC | 27/02/22 |
| Usonga United | 3 - 1 | TNS FC | 06/03/22 |
| TNS FC | 2 - 3 | Yakupa FC | 13/03/22 |
| Karapul Villa FC | 0 - 2 | TNS FC | 20/03/22 |
| TNS FC | 4 - 1 | Nyamlori FC | 27/03/22 |
| Power Boys FC | 3 - 0 | TNS FC | 03/04/22 |
| Amani Youth | 0 - 1 | TNS FC | 17/04/22 |
| TNS FC | 2 - 1 | Greenland FC | 24/04/22 |
| Kisian Rangers | 2 - 1 | TNS FC | 01/05/22 |
| TNS FC | 3 - 3 | Madiany FC | 08/05/22 |
| Madungu FC |
0 - 2
Walkover |
TNS FC | 15/05/22 |
| TNS FC | 3 - 3 | Manyatta Suncity | 22/05/22 |
| Oneno Nam FC | 2 - 0 | TNS FC | 29/05/22 |
| TNS FC |
0 - 0
Postponed |
Upper Hill FC | 19/06/22 |
| TNS FC | 1 - 2 | Oneno Nam FC | 10/07/22 |
| TNS FC | 4 - 1 | Madungu FC | 24/07/22 |
| TNS FC | 3 - 2 | Kisian Rangers | 07/08/22 |
| TNS FC | 1 - 1 | Amani Youth | 21/08/22 |
| TNS FC | 1 - 0 | Power Boys FC | 04/09/22 |
| Nyamlori FC | 3 - 2 | TNS FC | 11/09/22 |
| Greenland FC | 1 - 2 | TNS FC | 25/09/22 |
| TNS FC | 3 - 2 | Usonga United | 02/10/22 |
| Madiany FC | - | TNS FC | 02/10/22 |
| Yakupa FC |
2 - 0
Walkover |
TNS FC | 09/10/22 |
| Manyatta Suncity | - | TNS FC | 09/10/22 |
| Yieke FC | - | TNS FC | 22/10/22 |
| Upper Hill FC | - | TNS FC | 22/10/22 |
Karapul Villa FC
| Karapul Villa FC | 1 - 0 | Manyatta Suncity | 06/03/22 |
| Oneno Nam FC | 2 - 0 | Karapul Villa FC | 13/03/22 |
| Karapul Villa FC | 0 - 2 | TNS FC | 20/03/22 |
| Upper Hill FC | 1 - 1 | Karapul Villa FC | 27/03/22 |
| Karapul Villa FC | 0 - 1 | Usonga United | 03/04/22 |
| Yieke FC | 1 - 1 | Karapul Villa FC | 17/04/22 |
| Karapul Villa FC | 1 - 1 | Nyamlori FC | 24/04/22 |
| Power Boys FC |
2 - 0
Walkover |
Karapul Villa FC | 01/05/22 |
| Amani Youth | 2 - 1 | Karapul Villa FC | 15/05/22 |
| Karapul Villa FC | 2 - 1 | Greenland FC | 22/05/22 |
| Kisian Rangers |
2 - 0
Walkover |
Karapul Villa FC | 29/05/22 |
| Karapul Villa FC | 1 - 1 | Madiany FC | 05/06/22 |
| Madungu FC |
1 - 0
Postponed |
Karapul Villa FC | 12/06/22 |
| Yakupa FC | 1 - 0 | Karapul Villa FC | 19/06/22 |
| Karapul Villa FC | 2 - 0 | Kisian Rangers | 10/07/22 |
| Greenland FC | 0 - 1 | Karapul Villa FC | 17/07/22 |
| Karapul Villa FC | 2 - 4 | Amani Youth | 24/07/22 |
| Karapul Villa FC |
2 - 0
Walkover |
Yakupa FC | 28/08/22 |
| Usonga United | 0 - 0 | Karapul Villa FC | 04/09/22 |
| Karapul Villa FC | 0 - 1 | Oneno Nam FC | 25/09/22 |
| Nyamlori FC | 3 - 1 | Karapul Villa FC | 02/10/22 |
| Karapul Villa FC | 1 - 2 | Madungu FC | 05/10/22 |
| Madiany FC |
-
Madiany relegated |
Karapul Villa FC | 09/10/22 |
| Manyatta Suncity | - | Karapul Villa FC | 09/10/22 |
| Karapul Villa FC |
2 - 0
Walkover |
Power Boys FC | 15/10/22 |
| Karapul Villa FC |
-
Awarded to Karapul by LCC |
Yieke FC | 22/10/22 |
| Karapul Villa FC |
-
Walkover |
Upper Hill FC | 22/10/22 |
TNS FC prematch form
L W D W W L D L D W D L W W L W W L L W
Karapul Villa FC prematch form
? D W L W W L L D L W L L D D L D L L W
