Madungu FC
| Madungu FC | 0 - 1 | Amani Youth | 20/02/22 |
| Madungu FC | 1 - 2 | Nyamlori FC | 27/02/22 |
| Madungu FC | 2 - 0 | Power Boys FC | 13/03/22 |
| Greenland FC | 0 - 4 | Madungu FC | 03/04/22 |
| Madungu FC | 3 - 0 | Kisian Rangers | 10/04/22 |
| Madiany FC | 2 - 1 | Madungu FC | 17/04/22 |
| Madungu FC | 3 - 1 | Yieke FC | 24/04/22 |
| Madungu FC |
2 - 0
Walkover |
Manyatta Suncity | 01/05/22 |
| Oneno Nam FC | 3 - 0 | Madungu FC | 08/05/22 |
| Madungu FC |
0 - 2
Walkover |
TNS FC | 15/05/22 |
| Upper Hill FC | 3 - 3 | Madungu FC | 22/05/22 |
| Yakupa FC | 3 - 2 | Madungu FC | 05/06/22 |
| Madungu FC | 0 - 1 | Usonga United | 11/06/22 |
| Madungu FC | 1 - 0 | Yakupa FC | 03/07/22 |
| Usonga United | 1 - 1 | Madungu FC | 10/07/22 |
| TNS FC | 4 - 1 | Madungu FC | 24/07/22 |
| Madungu FC |
2 - 0
Walkover |
Oneno Nam FC | 31/07/22 |
| Kisian Rangers | 1 - 2 | Madungu FC | 28/08/22 |
| Madungu FC | 2 - 0 | Greenland FC | 04/09/22 |
| Amani Youth | 0 - 0 | Madungu FC | 11/09/22 |
| Yieke FC | - | Madungu FC | 25/09/22 |
| Power Boys FC | 1 - 1 | Madungu FC | 02/10/22 |
| Karapul Villa FC | 1 - 2 | Madungu FC | 05/10/22 |
| Nyamlori FC |
4 - 1
Postponed |
Madungu FC | 09/10/22 |
| Manyatta Suncity | - | Madungu FC | 09/10/22 |
| Madungu FC |
-
Madiany Relegated after missing 3 matches |
Madiany FC | 15/10/22 |
| Madungu FC | - | Upper Hill FC | 22/10/22 |
Karapul Villa FC
| Karapul Villa FC | 1 - 0 | Manyatta Suncity | 06/03/22 |
| Oneno Nam FC | 2 - 0 | Karapul Villa FC | 13/03/22 |
| Karapul Villa FC | 0 - 2 | TNS FC | 20/03/22 |
| Upper Hill FC | 1 - 1 | Karapul Villa FC | 27/03/22 |
| Karapul Villa FC | 0 - 1 | Usonga United | 03/04/22 |
| Yieke FC | 1 - 1 | Karapul Villa FC | 17/04/22 |
| Karapul Villa FC | 1 - 1 | Nyamlori FC | 24/04/22 |
| Power Boys FC |
2 - 0
Walkover |
Karapul Villa FC | 01/05/22 |
| Amani Youth | 2 - 1 | Karapul Villa FC | 15/05/22 |
| Karapul Villa FC | 2 - 1 | Greenland FC | 22/05/22 |
| Kisian Rangers |
2 - 0
Walkover |
Karapul Villa FC | 29/05/22 |
| Karapul Villa FC | 1 - 1 | Madiany FC | 05/06/22 |
| Yakupa FC | 1 - 0 | Karapul Villa FC | 19/06/22 |
| Karapul Villa FC | 2 - 0 | Kisian Rangers | 10/07/22 |
| Greenland FC | 0 - 1 | Karapul Villa FC | 17/07/22 |
| Karapul Villa FC | 2 - 4 | Amani Youth | 24/07/22 |
| Karapul Villa FC |
2 - 0
Walkover |
Yakupa FC | 28/08/22 |
| Usonga United | 0 - 0 | Karapul Villa FC | 04/09/22 |
| TNS FC | 0 - 2 | Karapul Villa FC | 18/09/22 |
| Karapul Villa FC | 0 - 1 | Oneno Nam FC | 25/09/22 |
| Nyamlori FC | 3 - 1 | Karapul Villa FC | 02/10/22 |
| Karapul Villa FC | 1 - 2 | Madungu FC | 05/10/22 |
| Madiany FC |
-
Madiany relegated |
Karapul Villa FC | 09/10/22 |
| Manyatta Suncity | - | Karapul Villa FC | 09/10/22 |
| Karapul Villa FC |
2 - 0
Walkover |
Power Boys FC | 15/10/22 |
| Karapul Villa FC |
-
Awarded to Karapul by LCC |
Yieke FC | 22/10/22 |
| Karapul Villa FC |
-
Walkover |
Upper Hill FC | 22/10/22 |
Madungu FC prematch form
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Karapul Villa FC prematch form
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