Homa Bay Rangers
| Dero FC | 1 - 0 | Homa Bay Rangers | 14/03/21 |
| Homa Bay Rangers | 4 - 1 | Kiamabundu FC | 21/03/21 |
| Homa Bay Rangers | 1 - 2 | Jets FC | 23/05/21 |
| Kambare Blackstars | 2 - 1 | Homa Bay Rangers | 30/05/21 |
| Homa Bay Rangers | 1 - 0 | Kibuye FC | 06/06/21 |
| Kisumu Green Berets |
2 - 0
Walkover |
Homa Bay Rangers | 13/06/21 |
| Homa Bay Rangers | 1 - 4 | Kobare Mobimba | 15/08/21 |
| Suba Stars | 0 - 1 | Homa Bay Rangers | 22/08/21 |
| Homa Bay Rangers | 1 - 1 | Team Kibos FC | 29/08/21 |
| Village Diamond | 0 - 0 | Homa Bay Rangers | 05/09/21 |
| Homa Bay Rangers | 1 - 0 | Village Diamond | 19/09/21 |
| Team Kibos FC | 1 - 1 | Homa Bay Rangers | 26/09/21 |
| Jets FC | 6 - 0 | Homa Bay Rangers | 02/10/21 |
| Homa Bay Rangers | 1 - 2 | Kambare Blackstars | 03/10/21 |
| Homa Bay Rangers | 1 - 0 | Kisumu Green Berets | 09/10/21 |
| Kobare Mobimba |
2 - 0
Walkover |
Homa Bay Rangers | 10/10/21 |
| Kiamabundu FC | 3 - 2 | Homa Bay Rangers | 16/10/21 |
| Homa Bay Rangers | 0 - 0 | Dero FC | 17/10/21 |
| White Hearts FC | 1 - 3 | Homa Bay Rangers | 20/10/21 |
| Homa Bay Rangers | 1 - 1 | Suba Stars | 23/10/21 |
| Kibuye FC |
-
Suspended |
Homa Bay Rangers | 24/10/21 |
White Hearts FC
| White Hearts FC | 1 - 1 | Jets FC | 14/03/21 |
| Kambare Blackstars | 0 - 0 | White Hearts FC | 21/03/21 |
| White Hearts FC | 0 - 0 | Kibuye FC | 23/05/21 |
| Kisumu Green Berets | 1 - 0 | White Hearts FC | 30/05/21 |
| White Hearts FC | 1 - 2 | Kobare Mobimba | 06/06/21 |
| Suba Stars | 1 - 0 | White Hearts FC | 13/06/21 |
| White Hearts FC | 1 - 2 | Team Kibos FC | 15/08/21 |
| Village Diamond | 2 - 1 | White Hearts FC | 22/08/21 |
| Kiamabundu FC | 2 - 2 | White Hearts FC | 29/08/21 |
| White Hearts FC | 0 - 0 | Dero FC | 05/09/21 |
| Dero FC | 2 - 0 | White Hearts FC | 19/09/21 |
| White Hearts FC | 2 - 0 | Kiamabundu FC | 26/09/21 |
| Kibuye FC |
-
Suspended |
White Hearts FC | 02/10/21 |
| White Hearts FC | 2 - 1 | Kisumu Green Berets | 03/10/21 |
| White Hearts FC |
2 - 0
Walkover |
Suba Stars | 09/10/21 |
| Team Kibos FC |
2 - 0
Walkover |
White Hearts FC | 10/10/21 |
| Jets FC | 0 - 2 | White Hearts FC | 17/10/21 |
| White Hearts FC | 1 - 3 | Homa Bay Rangers | 20/10/21 |
| White Hearts FC |
2 - 0
Walkover |
Village Diamond | 23/10/21 |
| Kobare Mobimba |
2 - 0
Walkover |
White Hearts FC | 24/10/21 |
| White Hearts FC |
2 - 0
Walkover |
Kambare Blackstars | 31/10/21 |
