Amani Youth
| Madungu FC | 0 - 1 | Amani Youth | 20/02/22 |
| Madiany FC | 0 - 1 | Amani Youth | 27/02/22 |
| Kisian Rangers | 0 - 3 | Amani Youth | 13/03/22 |
| Amani Youth | 0 - 1 | Manyatta Suncity | 03/04/22 |
| Oneno Nam FC | 1 - 0 | Amani Youth | 10/04/22 |
| Amani Youth | 0 - 1 | TNS FC | 17/04/22 |
| Upper Hill FC | 0 - 1 | Amani Youth | 24/04/22 |
| Yakupa FC | 1 - 2 | Amani Youth | 08/05/22 |
| Amani Youth | 2 - 1 | Karapul Villa FC | 15/05/22 |
| Nyamlori FC | 0 - 2 | Amani Youth | 22/05/22 |
| Amani Youth | 1 - 0 | Power Boys FC | 29/05/22 |
| Amani Youth |
3 - 0
Postponed |
Yieke FC | 01/06/22 |
| Amani Youth |
3 - 0
Postponed |
Greenland FC | 18/06/22 |
| Power Boys FC | 0 - 1 | Amani Youth | 10/07/22 |
| Amani Youth | 1 - 1 | Nyamlori FC | 17/07/22 |
| Karapul Villa FC | 2 - 4 | Amani Youth | 24/07/22 |
| Amani Youth | 0 - 0 | Yakupa FC | 31/07/22 |
| Usonga United | 0 - 1 | Amani Youth | 07/08/22 |
| TNS FC | 1 - 1 | Amani Youth | 21/08/22 |
| Amani Youth | 1 - 1 | Oneno Nam FC | 28/08/22 |
| Amani Youth | 0 - 0 | Madungu FC | 11/09/22 |
| Greenland FC |
2 - 0
Walkover |
Amani Youth | 24/09/22 |
| Amani Youth | 6 - 0 | Kisian Rangers | 25/09/22 |
| Yieke FC | - | Amani Youth | 02/10/22 |
| Amani Youth | - | Upper Hill FC | 22/10/22 |
| Amani Youth |
-
Madiany Relegated after missing 3 matches |
Madiany FC | 29/10/22 |
| Manyatta Suncity | - | Amani Youth | 29/10/22 |
Usonga United
| Usonga United | 3 - 1 | TNS FC | 06/03/22 |
| Upper Hill FC | 2 - 0 | Usonga United | 13/03/22 |
| Yieke FC | 1 - 2 | Usonga United | 20/03/22 |
| Usonga United | 2 - 0 | Yakupa FC | 27/03/22 |
| Karapul Villa FC | 0 - 1 | Usonga United | 03/04/22 |
| Usonga United | 0 - 1 | Nyamlori FC | 10/04/22 |
| Power Boys FC | 2 - 1 | Usonga United | 17/04/22 |
| Usonga United | 3 - 0 | Greenland FC | 08/05/22 |
| Kisian Rangers | 1 - 1 | Usonga United | 15/05/22 |
| Usonga United | 1 - 2 | Madiany FC | 22/05/22 |
| Usonga United |
2 - 0
Walkover |
Manyatta Suncity | 05/06/22 |
| Madungu FC | 0 - 1 | Usonga United | 11/06/22 |
| Oneno Nam FC |
1 - 0
Postponed |
Usonga United | 12/06/22 |
| Usonga United | 1 - 1 | Madungu FC | 10/07/22 |
| Usonga United | 1 - 1 | Kisian Rangers | 24/07/22 |
| Greenland FC | 0 - 4 | Usonga United | 31/07/22 |
| Usonga United | 0 - 1 | Amani Youth | 07/08/22 |
| Usonga United |
2 - 0
Walkover |
Power Boys FC | 21/08/22 |
| Nyamlori FC |
2 - 0
Walkover |
Usonga United | 28/08/22 |
| Usonga United | 0 - 0 | Karapul Villa FC | 04/09/22 |
| Yakupa FC | 0 - 1 | Usonga United | 11/09/22 |
| TNS FC | 3 - 2 | Usonga United | 02/10/22 |
| Manyatta Suncity | - | Usonga United | 09/10/22 |
| Usonga United | 0 - 3 | Oneno Nam FC | 09/10/22 |
| Madiany FC | - | Usonga United | 09/10/22 |
| Usonga United | - | Upper Hill FC | 22/10/22 |
| Usonga United | - | Yieke FC | 22/10/22 |
Amani Youth prematch form
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Usonga United prematch form
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