Nyamlori FC
| Power Boys FC | 0 - 1 | Nyamlori FC | 14/03/21 |
| Nyamlori FC | 2 - 1 | Masawa FC | 21/03/21 |
| Super Strikers FC | 0 - 1 | Nyamlori FC | 22/05/21 |
| Nyamlori FC | 2 - 1 | Tido FC | 29/05/21 |
| Kianja Allstars FC | 1 - 3 | Nyamlori FC | 05/06/21 |
| Winam FC | 0 - 3 | Nyamlori FC | 14/08/21 |
| Nyamlori FC | 2 - 1 | Kolwa Allstars | 15/08/21 |
| Kolwa United |
0 - 0
played |
Nyamlori FC | 21/08/21 |
| Nyamlori FC | 0 - 0 | Orongo FC | 22/08/21 |
| Slum Totos FC | 0 - 1 | Nyamlori FC | 28/08/21 |
| The Saints FC | 0 - 0 | Nyamlori FC | 04/09/21 |
| Kunya FC | 0 - 6 | Nyamlori FC | 11/09/21 |
| Julu Nyabangu FC |
0 - 2
Julu Nyabangu refused to play |
Nyamlori FC | 12/09/21 |
| Nyamlori FC |
-
2-0 walkover nullified |
Kunya FC | 25/09/21 |
| Masawa FC | 1 - 3 | Nyamlori FC | 26/09/21 |
| Nyamlori FC | 2 - 1 | The Saints FC | 02/10/21 |
| Nyamlori FC | 1 - 0 | Power Boys FC | 03/10/21 |
| Nyamlori FC | 1 - 1 | Julu Nyabangu FC | 09/10/21 |
| Kisumu City Stars | 0 - 2 | Nyamlori FC | 10/10/21 |
| Nyamlori FC | 0 - 2 | Slum Totos FC | 16/10/21 |
| Tido FC | 0 - 3 | Nyamlori FC | 17/10/21 |
| Nyamlori FC | 1 - 1 | Winam FC | 20/10/21 |
| Orongo FC | 1 - 2 | Nyamlori FC | 23/10/21 |
| Nyamlori FC | 3 - 1 | Kianja Allstars FC | 24/10/21 |
| Nyamlori FC |
2 - 0
Walkover |
Super Strikers FC | 31/10/21 |
| Kolwa Allstars | 0 - 0 | Nyamlori FC | 06/11/21 |
| Nyamlori FC | 1 - 0 | Kolwa United | 14/11/21 |
Kisumu City Stars
| Kolwa United | 0 - 2 | Kisumu City Stars | 06/06/21 |
| Kisumu City Stars | 0 - 0 | Kianja Allstars FC | 13/06/21 |
| The Saints FC | 1 - 2 | Kisumu City Stars | 14/08/21 |
| Kisumu City Stars | 4 - 1 | Slum Totos FC | 15/08/21 |
| Kunya FC |
0 - 2
Walkover |
Kisumu City Stars | 21/08/21 |
| Kisumu City Stars | 2 - 1 | Power Boys FC | 22/08/21 |
| Super Strikers FC | 1 - 2 | Kisumu City Stars | 28/08/21 |
| Orongo FC | 0 - 2 | Kisumu City Stars | 04/09/21 |
| Kisumu City Stars |
1 - 0
Suspended |
Tido FC | 05/09/21 |
| Masawa FC | 0 - 1 | Kisumu City Stars | 11/09/21 |
| Kolwa Allstars | 1 - 1 | Kisumu City Stars | 12/09/21 |
| Kisumu City Stars | 3 - 0 | Julu Nyabangu FC | 18/09/21 |
| Kisumu City Stars | 3 - 0 | Winam FC | 19/09/21 |
| Kisumu City Stars | 0 - 0 | Orongo FC | 25/09/21 |
| Tido FC | 0 - 0 | Kisumu City Stars | 26/09/21 |
| Julu Nyabangu FC | 1 - 0 | Kisumu City Stars | 02/10/21 |
| Kianja Allstars FC | 1 - 0 | Kisumu City Stars | 09/10/21 |
| Kisumu City Stars | 0 - 2 | Nyamlori FC | 10/10/21 |
| Kisumu City Stars | 5 - 1 | Super Strikers FC | 16/10/21 |
| Kisumu City Stars | 4 - 1 | Masawa FC | 17/10/21 |
| Kisumu City Stars | 2 - 2 | The Saints FC | 20/10/21 |
| Power Boys FC | 1 - 2 | Kisumu City Stars | 23/10/21 |
| Kisumu City Stars | 5 - 4 | Kolwa United | 24/10/21 |
| Kisumu City Stars |
-
Suspended |
Kunya FC | 30/10/21 |
| Slum Totos FC | 1 - 3 | Kisumu City Stars | 31/10/21 |
| Winam FC | 1 - 2 | Kisumu City Stars | 06/11/21 |
| Kisumu City Stars | 0 - 0 | Kolwa Allstars | 13/11/21 |
Nyamlori FC prematch form
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Kisumu City Stars prematch form
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