Nyamlori FC
| Power Boys FC | 0 - 1 | Nyamlori FC | 14/03/21 |
| Nyamlori FC | 2 - 1 | Masawa FC | 21/03/21 |
| Super Strikers FC | 0 - 1 | Nyamlori FC | 22/05/21 |
| Nyamlori FC | 2 - 1 | Tido FC | 29/05/21 |
| Kianja Allstars FC | 1 - 3 | Nyamlori FC | 05/06/21 |
| Winam FC | 0 - 3 | Nyamlori FC | 14/08/21 |
| Nyamlori FC | 2 - 1 | Kolwa Allstars | 15/08/21 |
| Kolwa United |
0 - 0
played |
Nyamlori FC | 21/08/21 |
| Slum Totos FC | 0 - 1 | Nyamlori FC | 28/08/21 |
| Nyamlori FC | 1 - 0 | Kisumu City Stars | 29/08/21 |
| The Saints FC | 0 - 0 | Nyamlori FC | 04/09/21 |
| Kunya FC | 0 - 6 | Nyamlori FC | 11/09/21 |
| Julu Nyabangu FC |
0 - 2
Julu Nyabangu refused to play |
Nyamlori FC | 12/09/21 |
| Nyamlori FC |
-
2-0 walkover nullified |
Kunya FC | 25/09/21 |
| Masawa FC | 1 - 3 | Nyamlori FC | 26/09/21 |
| Nyamlori FC | 2 - 1 | The Saints FC | 02/10/21 |
| Nyamlori FC | 1 - 0 | Power Boys FC | 03/10/21 |
| Nyamlori FC | 1 - 1 | Julu Nyabangu FC | 09/10/21 |
| Kisumu City Stars | 0 - 2 | Nyamlori FC | 10/10/21 |
| Nyamlori FC | 0 - 2 | Slum Totos FC | 16/10/21 |
| Tido FC | 0 - 3 | Nyamlori FC | 17/10/21 |
| Nyamlori FC | 1 - 1 | Winam FC | 20/10/21 |
| Orongo FC | 1 - 2 | Nyamlori FC | 23/10/21 |
| Nyamlori FC | 3 - 1 | Kianja Allstars FC | 24/10/21 |
| Nyamlori FC |
2 - 0
Walkover |
Super Strikers FC | 31/10/21 |
| Kolwa Allstars | 0 - 0 | Nyamlori FC | 06/11/21 |
| Nyamlori FC | 1 - 0 | Kolwa United | 14/11/21 |
Orongo FC
| Orongo FC | 1 - 0 | Slum Totos FC | 20/03/21 |
| Julu Nyabangu FC | 0 - 1 | Orongo FC | 22/05/21 |
| Orongo FC | 1 - 0 | The Saints FC | 29/05/21 |
| Power Boys FC | 1 - 2 | Orongo FC | 06/06/21 |
| Orongo FC | 2 - 1 | Masawa FC | 13/06/21 |
| Kolwa United | 1 - 0 | Orongo FC | 14/08/21 |
| Tido FC | 1 - 1 | Orongo FC | 15/08/21 |
| Orongo FC | 0 - 1 | Kianja Allstars FC | 21/08/21 |
| Orongo FC | 2 - 1 | Winam FC | 28/08/21 |
| Kolwa Allstars | 2 - 0 | Orongo FC | 29/08/21 |
| Orongo FC | 0 - 2 | Kisumu City Stars | 04/09/21 |
| Kunya FC | 0 - 1 | Orongo FC | 12/09/21 |
| Super Strikers FC | 0 - 8 | Orongo FC | 19/09/21 |
| Kisumu City Stars | 0 - 0 | Orongo FC | 25/09/21 |
| Slum Totos FC | 2 - 0 | Orongo FC | 26/09/21 |
| Orongo FC | 2 - 0 | Julu Nyabangu FC | 03/10/21 |
| Orongo FC | 0 - 2 | Kolwa Allstars | 09/10/21 |
| Masawa FC | 0 - 0 | Orongo FC | 10/10/21 |
| Winam FC | 5 - 1 | Orongo FC | 16/10/21 |
| Orongo FC |
-
Suspended |
Kunya FC | 17/10/21 |
| Orongo FC | 1 - 2 | Kolwa United | 20/10/21 |
| Orongo FC | 1 - 2 | Nyamlori FC | 23/10/21 |
| Orongo FC | 0 - 2 | Power Boys FC | 24/10/21 |
| Kianja Allstars FC | 1 - 2 | Orongo FC | 30/10/21 |
| The Saints FC | 4 - 1 | Orongo FC | 31/10/21 |
| Orongo FC | 3 - 1 | Tido FC | 07/11/21 |
| Orongo FC | 0 - 1 | Super Strikers FC | 14/11/21 |
Nyamlori FC prematch form
D W W W W W W W
Orongo FC prematch form
L D L W W W W W
