Itierio FC
| Super Warriors | 3 - 0 | Itierio FC | 27/02/22 |
| Itierio FC | 2 - 0 | Wazoefu FC | 06/03/22 |
| Aspire FC | 1 - 1 | Itierio FC | 12/03/22 |
| Itierio FC | 0 - 1 | Bobaracho FC | 20/03/22 |
| Itierio FC | - | Gianchere Friends | 20/03/22 |
| Gunners FC | 1 - 1 | Itierio FC | 27/03/22 |
| Itierio FC | 2 - 0 | Kisii United FC | 09/04/22 |
| KRK FC | 0 - 2 | Itierio FC | 16/04/22 |
| Itierio FC | 3 - 0 | Mwembe FC | 23/04/22 |
| Nubia Kings FC | 3 - 1 | Itierio FC | 15/05/22 |
| Itierio FC | 2 - 0 | Nyamage FC | 05/06/22 |
| Mwembe FC | 2 - 1 | Itierio FC | 09/07/22 |
| Itierio FC | 2 - 2 | KRK FC | 17/07/22 |
| Kisii United FC | 1 - 0 | Itierio FC | 24/07/22 |
| Bobaracho FC | 4 - 2 | Itierio FC | 06/08/22 |
| Itierio FC | 5 - 2 | Gunners FC | 07/08/22 |
| Gianchere Friends | - | Itierio FC | 14/08/22 |
| Wazoefu FC | 0 - 2 | Itierio FC | 28/08/22 |
| Itierio FC | 0 - 1 | Super Warriors | 03/09/22 |
| Nyamage FC | 0 - 0 | Itierio FC | 11/09/22 |
| Itierio FC | 2 - 1 | Nubia Kings FC | 17/09/22 |
| Itierio FC | 2 - 3 | Aspire FC | 24/09/22 |
Kisii United FC
| Nyamage FC | 0 - 2 | Kisii United FC | 27/02/22 |
| Kisii United FC | 1 - 0 | Super Warriors | 05/03/22 |
| Wazoefu FC | 5 - 1 | Kisii United FC | 13/03/22 |
| Kisii United FC | 1 - 4 | Aspire FC | 20/03/22 |
| Bobaracho FC | 1 - 2 | Kisii United FC | 26/03/22 |
| Gianchere Friends | - | Kisii United FC | 26/03/22 |
| Kisii United FC | 2 - 2 | Gunners FC | 03/04/22 |
| Itierio FC | 2 - 0 | Kisii United FC | 09/04/22 |
| Kisii United FC | 3 - 2 | KRK FC | 01/05/22 |
| Nubia Kings FC | 1 - 0 | Kisii United FC | 08/05/22 |
| Mwembe FC | 2 - 0 | Kisii United FC | 04/06/22 |
| KRK FC | 1 - 4 | Kisii United FC | 10/07/22 |
| Kisii United FC | 0 - 1 | Bobaracho FC | 17/07/22 |
| Kisii United FC | 1 - 0 | Itierio FC | 24/07/22 |
| Kisii United FC | - | Gianchere Friends | 06/08/22 |
| Gunners FC |
2 - 0
Walkover |
Kisii United FC | 06/08/22 |
| Aspire FC | - | Kisii United FC | 14/08/22 |
| Kisii United FC | - | Wazoefu FC | 20/08/22 |
| Super Warriors | 5 - 1 | Kisii United FC | 28/08/22 |
| Kisii United FC |
0 - 2
Walkover |
Nyamage FC | 04/09/22 |
| Kisii United FC | 1 - 1 | Nubia Kings FC | 10/09/22 |
| Kisii United FC | 0 - 1 | Mwembe FC | 18/09/22 |
Itierio FC prematch form
L W D L W ? W L L D L W L W W W D ? L D W L
Kisii United FC prematch form
L D L L ? ? L ? W L W L L W L D ? W L L W W
