Lugulu FC
| Lugulu FC | 1 - 0 | Mihiu United FC | 31/01/21 |
| Rosterman United FC | 2 - 2 | Lugulu FC | 07/02/21 |
| Lugulu FC | 0 - 2 | Shaviringa United | 14/02/21 |
| Busia Sugar FC |
-
0-0 result nullified |
Lugulu FC | 21/02/21 |
| The Rock Saints FC |
-
3-1 result nullified |
Lugulu FC | 28/02/21 |
| Lugulu FC | 0 - 2 | Bungoma Alters FC | 07/03/21 |
| Compel FC | 1 - 0 | Lugulu FC | 14/03/21 |
| Lugulu FC |
-
0-0 result nullified |
Lakeview FC | 24/03/21 |
| Mayanja Bullets FC |
-
1-4 result nullified |
Lugulu FC | 15/05/21 |
| Lugulu FC | 1 - 3 | Mayenje Santos FC | 22/05/21 |
| Kipsis Arrows FC | 0 - 1 | Lugulu FC | 29/05/21 |
| Lugulu FC | 1 - 1 | Luanda Sportiff | 05/06/21 |
| Butali Sugar FC | 1 - 1 | Lugulu FC | 12/06/21 |
| Lugulu FC | 0 - 1 | Busia Olympic | 14/08/21 |
| Lugulu FC | 1 - 0 | Legend FC | 21/08/21 |
| Lumakanda Combined |
0 - 2
Awarded to Lugulu |
Lugulu FC | 28/08/21 |
| Shooting Stars FC | 2 - 2 | Lugulu FC | 08/09/21 |
| Lugulu FC |
2 - 0
Abandoned |
Vihiga Sportiff FC | 19/09/21 |
| Lugulu FC | 1 - 1 | Shooting Stars FC | 26/09/21 |
| Luanda Sportiff | 1 - 1 | Lugulu FC | 28/09/21 |
| Lugulu FC | 1 - 1 | Kipsis Arrows FC | 02/10/21 |
| Mayenje Santos FC |
2 - 0
Walkover |
Lugulu FC | 05/10/21 |
| Busia Olympic |
2 - 0
Awarded to Busia Olympic |
Lugulu FC | 09/10/21 |
| Shaviringa United |
2 - 0
Walkover |
Lugulu FC | 12/10/21 |
| Lugulu FC | 2 - 0 | Butali Sugar FC | 17/10/21 |
| Lugulu FC |
2 - 0
Walkover |
Rosterman United FC | 20/10/21 |
| Young Stars FC |
-
Suspended |
Lugulu FC | 02/11/21 |
| Lugulu FC |
-
Suspended |
Compel FC | 09/11/21 |
| Vihiga Sportiff FC |
-
Suspended |
Lugulu FC | 13/11/21 |
| Legend FC |
-
Suspended |
Lugulu FC | 16/11/21 |
| Bungoma Alters FC |
-
Suspended |
Lugulu FC | 20/11/21 |
| Mihiu United FC |
-
Suspended |
Lugulu FC | 27/11/21 |
| Lugulu FC |
-
Suspended |
Lumakanda Combined | 12/12/21 |
Young Stars FC
| Busia Olympic | 1 - 0 | Young Stars FC | 30/01/21 |
| Shooting Stars FC | 0 - 1 | Young Stars FC | 06/02/21 |
| Young Stars FC | 2 - 1 | Vihiga Sportiff FC | 13/02/21 |
| Mihiu United FC | 1 - 0 | Young Stars FC | 20/02/21 |
| Young Stars FC | 0 - 0 | Rosterman United FC | 27/02/21 |
| Shaviringa United | 0 - 0 | Young Stars FC | 07/03/21 |
| Young Stars FC |
-
0-2 result nullified |
Busia Sugar FC | 14/03/21 |
| The Rock Saints FC |
-
2-2 result nullified |
Young Stars FC | 24/03/21 |
| Young Stars FC | 1 - 0 | Bungoma Alters FC | 16/05/21 |
| Compel FC |
0 - 2
Walkover |
Young Stars FC | 23/05/21 |
| Lakeview FC |
-
2-1 result nullified |
Young Stars FC | 30/05/21 |
| Young Stars FC |
-
2-1 result nullified |
Mayanja Bullets FC | 06/06/21 |
| Mayenje Santos FC | 3 - 0 | Young Stars FC | 13/06/21 |
| Young Stars FC | 2 - 3 | Kipsis Arrows FC | 15/08/21 |
| Luanda Sportiff | 0 - 0 | Young Stars FC | 22/08/21 |
| Young Stars FC | 0 - 2 | Butali Sugar FC | 28/08/21 |
| Young Stars FC | 0 - 1 | Legend FC | 08/09/21 |
| Lumakanda Combined | 0 - 2 | Young Stars FC | 18/09/21 |
| Butali Sugar FC | 1 - 2 | Young Stars FC | 25/09/21 |
| Bungoma Alters FC | 1 - 0 | Young Stars FC | 28/09/21 |
| Young Stars FC | 2 - 1 | Compel FC | 03/10/21 |
| Young Stars FC | 0 - 2 | Shaviringa United | 06/10/21 |
| Vihiga Sportiff FC | 5 - 0 | Young Stars FC | 09/10/21 |
| Young Stars FC | 3 - 3 | Lumakanda Combined | 13/10/21 |
| Rosterman United FC | 0 - 1 | Young Stars FC | 17/10/21 |
| Young Stars FC | 1 - 2 | Busia Olympic | 20/10/21 |
| Young Stars FC |
-
Suspended |
Lugulu FC | 02/11/21 |
| Young Stars FC |
-
Suspended |
Shooting Stars FC | 06/11/21 |
| Legend FC |
-
Suspended |
Young Stars FC | 09/11/21 |
| Kipsis Arrows FC |
-
Suspended |
Young Stars FC | 16/11/21 |
| Young Stars FC |
-
Suspended |
Mihiu United FC | 20/11/21 |
| Young Stars FC |
-
Suspended |
Mayenje Santos FC | 23/11/21 |
| Young Stars FC |
-
Suspended |
Luanda Sportiff | 27/11/21 |
Lugulu FC prematch form
W W L D D W L ? ? L L ? ? L D W
Young Stars FC prematch form
L D L L ? ? W W ? ? D D L W W L
